clopidogrel

Objective Aim To synthesis ortho - chlorophenylglycine as a reaction agent for prepartion of ADP receptor antagonist Clopidogrel.

目的合成二磷酸腺苷(ADP)受体拮抗剂氯吡格雷的原料dl-邻氯苯基甘氨酸.

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Conclusion: Atorvastatin, which is metabolited through the cytochrome P 450 ( CYP ) 3 A 4 Pathway, does not inhibits the antiplatelet activity of clopidogrel.

结论: 经细胞色素P4503A4 ( CYP3A4 ) 途径代谢的阿托伐他汀不抑制氯吡格雷的抗血小板活性.

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Aim To improve the synthetic procedure of clopidogrel, a platelet aggregation inhibitor.

目的改进抗血栓药物氯吡格雷硫酸氢盐的合成工艺.

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Objective To investigate the therapeutic effect of clopidogrel on progressive ischemic cerebral apoplexy.

目的研究氯吡格雷治疗进展型缺血性脑卒中的疗效.

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Methods: Sixty patients with HPPR after a 300 - mg loading dose of clopidogrel were enrolled.

方法: 60名服用负荷量300mg氯吡格雷后仍有HPPR的病人入选研究.

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Whether platelet inhibition can be enhanced by increasing clopidogrel maintenance dosage in T 2 DM patients is unknown.

在T2DM病人中增加氯比格雷的维持剂量是否能增强血小板抑制率尚不清楚.

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The difference was primarily due to a reduction in the rate of stroke with clopidogrel.

两组间差异主要源于使用氯吡格雷减低中风发生率.

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